Nuclear Medicine

At Prince Court Medical Centre, we offer a wide range of nuclear medicine services, to assist in diagnostic and treatment planning. These services utilise advanced technology and radiopharmaceuticals to visualise and evaluate organ function, disease processes, and therapeutic interventions. 

Our nuclear medicine services are divided into Gamma Camera Diagnostic Services, PET-CT Diagnostic Services and Nuclear Medicine Therapy Services. Each category provides unique benefits in terms of diagnostic imaging and the treatment of various medical conditions.

Gamma Camera-Based Nuclear Medicine Services

Gamma Camera imaging is a non-invasive diagnostic technique that uses a special camera to capture images of the internal organs and tissues based on the radiation emitted by a radiotracer injected into the patient. These images can reveal functional and physiological abnormalities.

1. Bone Scans
• 3-Phase Bone Scan
• Total Body Bone Scan (MDP)

2. Gastrointestinal (GI) Imaging
• GIT Bleed (Tc 99m RBC)
• GIT Transit / Emptying Studies (Tin Colloid)
• Hepatobiliary (HIDA) Scan
• Meckel's Diverticulum (Tc 99m)

3. Renal Imaging
• Renal DMSA (Morphology)
• Renal DTPA (Captopril Challenge)
• Renal Function (DTPA and MAG3)

4. Cardiac Imaging
• Myocardial Perfusion Imaging
• Myocardial Viability Study

5. Thyroid Imaging
• Thyroid Scan (Tc 99m)

6. Parathyroid Imaging
• Parathyroid Scan (Tc 99m MIBI)

7. Lymphatic Imaging
• Lymphoscintigraphy

8. Lung Perfusion Imaging
• Lung Perfusion Scan (MAA)

PET-CT-Based Nuclear Medicine Services

PET-CT is a powerful imaging tool used for cancer screening and staging. By combining positron emission tomography (PET) and computed tomography (CT), we can visualise the metabolic activity and anatomical structures of the body, aiding in the detection and assessment of cancerous cells.

1. FDG-PET/CT
• Cancer detection
• Staging
• Treatment response assessment
• Surveillance
• Infection/inflammation identification
• Tissue characterization
• Identification of biopsy site

2. DOTATATE PET/CT
• Neuroendocrine Tumor imaging
• Staging
• Treatment planning

3. GA-68 PSMA PET/CT
• Prostate cancer detection
• Staging
• Biochemical recurrence detection
• Treatment planning

4. FAPI PET/CT
• Pancreatic cancer imaging
• Sarcoma imaging
• Treatment response assessment
• Investigational use

Nuclear Medicine Therapy Services

Our Nuclear Medicine Therapy Services involve the use of radiopharmaceuticals to treat various diseases, particularly cancers and thyroid disorders. These therapies use radioactive materials that target specific cells or tissues, delivering localized radiation to treat abnormal growths and tumours.

1. Radioiodine Therapy
• Hyperthyroidism (Thyrotoxicosis or Toxic Nodular Goiter)
• Well-differentiated thyroid cancer

2. Radiosynovectomy Therapy
   Indications for RSV in patients with refractory synoviopathy:
1. Haemarthropathy: haemophilia
2. Arthritis:
   • Rheumatoid arthritis
   • Other accompanied inflammatory joint diseases, e.g., Lyme disease, Behcet’s disease, psoriatic arthritis, ankylosing spondylitis
3. Exudative synoviopathy:
   • Exudative osteoarthrosis
   • Postoperative effusion
4. Villonodular synovitis
5. Relapsing synovitis after surgical synovitis
6. Inoperable or multi-morbid patients with clinically relevant synovitis

3. Selective Internal Radiation Therapy (SIRT)
• SIRT - Yttrium-90 (SIRTEX)

4. Lutetium-177 PSMA
• Metastatic castration-resistant prostate cancer
• Histologically detected prostate cancer
• Non-resectable metastasis
• Tumor progression despite standard therapy

5. Lutetium-177 PRRT
• Metastatic or locally advanced, unresectable neuroendocrine tumour
• Disease progression in neuroendocrine tumour
• Pheochromocytoma, paraganglioma, neuroblastoma unsuitable for I-131 MIBG

6. I-131 – MIBG
• Inoperable pheochromocytoma, paraganglioma, malignant carcinoid tumour
• Stage III / IV neuroblastoma
• Metastatic or recurrent medullary thyroid cancer